Garlic and cancer prevention

Garlic intake and cancer risk: an analysis using the Food and Drug Administration’s evidence-based review system for the scientific evaluation of health claims.

A literature search found 19 human studies that were reviewed. Garlic in the diet did not reduce the risk of gastric, breast, lung, or endometrial cancer.
There is very limited evidence for a reduced risk of colon, prostate, esophageal, larynx, oral, ovary, or renal cell cancers.

Am J Clin Nutr. 2009 Jan;89(1):257-64. Epub 2008 Dec 3.
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Colorectal cancer prevention

The potential for prevention of colorectal cancer in the UK.

“We estimate that 31.5% of cancers in men and 18.4% in women could be prevented if reasonable targets with respect to diet (reduced consumption of red meat, increased fruit and vegetables), exercise (30 min 5 days a week), alcohol consumption (3 U a day for men, 2 U for women) and weight control were achieved.”

Eur J Cancer Prev. 2009 Feb 20.

Energy intake, physical activity and cancer

Energy intake, physical activity, energy balance, and cancer: epidemiologic evidence.

Obesity increases the risk of cancers of

  • colon and rectum
  • breast (in postmenopausal women)
  • endometrium (lining of the uterus)
  • kidney (renal cell)
  • esophagus (adenocarcinoma).

Obesity probably increases cancers of

  • pancreas
  • liver
  • gallbladder
  • aggressive prostate cancer.
Methods Mol Biol. 2009;472:191-215.

Impact of Nutrition and Exercise on Cancer Survival

Impact of nutrition and exercise on cancer survival.

Observational data strongly indicate that obesity, weight gain, and physical inactivity are adverse prognostic factors, although data on diet or supplement use in relation to cancer survival are more limited and inconsistent.

Cancer J. 2008 Nov-Dec;14(6):435-41.
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Dietary flavonoids and cancer risk

Dietary intake of selected flavonols, flavones, and flavonoid-rich foods and risk of cancer in middle-aged and older women.

Five flavonoid containing foods (tea, apple, broccoli, onion, and tofu) did not prevent cancer after 11.5 years in over 38,000 women in the Women’s Health Study.

Am J Clin Nutr. 2009 Jan 21.

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Diet and upper-aerodigestive tract cancer

Diet and upper-aerodigestive tract cancer in Europe: The ARCAGE study.

Eating red meat increased upper-aerodigestive tract cancer risk, especially esophageal cancer.
The consumption of fruits, vegetables, olive oil and tea reduced the risk of upper-aerodigestive tract cancer.

Int J Cancer. 2008 Dec 23.

Fruits and vegetables may prevent colorectal cancer

Fruit and vegetable intakes are associated with lower risk of colorectal adenomas.

“This study provides additional evidence that high total fruit intake and certain fruit and vegetable intakes may be associated with a reduced risk of colorectal adenomas.”

J Nutr. 2009 Feb;139(2):340-4. Epub 2008 Dec 17.

Fruits and vegetables, breast cancer risk, hormone receptor status

Intake of fruits, and vegetables in relation to breast cancer risk by hormone receptor status.

A large population-based case-control study from Poland.
An increased level of total fruit intake was associated with a reduced overall risk of breast cancer. This association was stronger for reduced estrogen receptor positive tumors.
Increased vegetable intake did not affect the risk of breast cancer.

Breast Cancer Res Treat. 2008 Jan;107(1):113-7.


Diet and breast cancer risk

Impact of diet on breast cancer risk.

Studies so far have only shown “consistent and strong positive associations” for an increased breast cancer risk with alcohol intake and being overweight.

Curr Opin Obstet Gynecol. 2009 Feb;21(1):80-5.
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